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Sickle Cell Disease

 Sickle Cell Disease

Sickle Cell Disease (SCD) is a hereditary blood disorder caused by a mutation in the hemoglobin gene, leading to the production of abnormal hemoglobin S. This abnormal hemoglobin causes red blood cells to become rigid and crescent-shaped, reducing their ability to carry oxygen efficiently. The distorted cells can block small blood vessels, resulting in painful episodes (vaso-occlusive crises), chronic anemia, infections, organ damage, and reduced life expectancy. SCD is inherited in an autosomal recessive pattern and is most prevalent among individuals of African, Middle Eastern, Mediterranean, and South Asian descent. Advances in newborn screening, supportive care, gene therapy, and stem cell transplantation have significantly improved disease management and patient outcomes.

Sickle Cell Disease, Hemoglobin S, Genetic Blood Disorder, Red Blood Cell Deformation, Chronic Anemia, Vaso-Occlusive Crisis, Inherited Hemoglobinopathy, Bone Marrow Transplantation, Gene Therapy, Newborn Screening

#SickleCellDisease #GeneticDisorders #Hemoglobinopathy #BloodDisorders #InheritedDiseases #AnemiaAwareness #RareDiseases #PublicHealth #GeneTherapy #MedicalResearch

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