Skip to main content

Polymeric Gene Interaction

 Polymeric Gene Interaction

Polymeric gene interaction refers to the combined effect of two or more genes that contribute additively or synergistically to the expression of a single quantitative trait. Unlike epistasis, where one gene masks the effect of another, polymeric genes independently influence the phenotype, and their cumulative action determines trait intensity. This type of interaction is commonly observed in complex traits such as height, skin color, yield potential, disease susceptibility, and stress tolerance. Polymeric gene interactions play a crucial role in quantitative genetics, population genetics, plant and animal breeding, and human disease research, helping scientists understand multifactorial inheritance patterns and polygenic disorders.

Polymeric gene interaction, Polygenic inheritance, Quantitative traits, Additive gene effect, Gene–gene interaction, Multifactorial inheritance, Complex traits, Genetic architecture, Phenotypic variation, Quantitative genetics

#PolymericGenes #GeneInteraction #PolygenicInheritance #QuantitativeGenetics #ComplexTraits #GenomicsResearch #MolecularGenetics #TraitInheritance #GeneticVariation #BiomedicalGenomics

International Conference on Genetics and Genomics of Diseases 

Visit: genetics-conferences.healthcarek.com

Award Nomination: genetics-conferences.healthcarek.com/award-nomination/?ecategory=Awards&rcategory=Awardee

Award registration: genetics-conferences.healthcarek.com/award-registration/ 

For Enquiries: support@healthcarek.com 

Get Connected Here 
--------------------------------- 
--------------------------------- 
in.pinterest.com/Dorita0211 
twitter.com/Dorita_02_11_ 
facebook.com/profile.php?id=61555903296992 
instagram.com/p/C4ukfcOsK36 
genetics-awards.blogspot.com/
youtube.com/@GeneticsHealthcare
linkedin.com/in/genetics-research-160337363/

Comments

Post a Comment

Popular posts from this blog

Fruitful innovation

Fruitful innovation: Transforming watermelon genetics with advanced base editors The development of new adenine base editors (ABE) and adenine-to-thymine/ guanine base editors (AKBE) is transforming watermelon genetic engineering. These innovative tools enable precise A:T-to-G and A:T-to-T base substitutions, allowing for targeted genetic modifications. The research highlights the efficiency of these editors in generating specific mutations, such as a flowerless phenotype in ClFT (Y84H) mutant plants. This advancement not only enhances the understanding of gene function but also significantly improves molecular breeding, paving the way for more efficient watermelon crop improvement. Traditional breeding methods for watermelon often face challenges in achieving desired genetic traits efficiently and accurately. While CRISPR/Cas9 has provided a powerful tool for genome editing, its precision and scope are sometimes limited. These limitations highlight the need for more advanced gene-e...
Post a Comment
Read more

Genetic factors with clinical trial stoppage

Genetic factors associated with reasons for clinical trial stoppage Many drug discovery projects are started but few progress fully through clinical trials to approval. Previous work has shown that human genetics support for the therapeutic hypothesis increases the chance of trial progression. Here, we applied natural language processing to classify the free-text reasons for 28,561 clinical trials that stopped before their endpoints were met. We then evaluated these classes in light of the underlying evidence for the therapeutic hypothesis and target properties. We found that trials are more likely to stop because of a lack of efficacy in the absence of strong genetic evidence from human populations or genetically modified animal models. Furthermore, certain trials are more likely to stop for safety reasons if the drug target gene is highly constrained in human populations and if the gene is broadly expressed across tissues. These results support the growing use of human genetics to ...
Post a Comment
Read more

Genetic Test

Genetic test eliminates progressive retinal atrophy in English shepherd dogs Researchers at the University of Cambridge recently published their findings in Genes after identifying the genetic mutation that is causing progressive retinal atrophy (PRA) in English shepherd dogs. PRA is a group of inherited diseases causing progressive degeneration of the light sensitive cells within the back of the eyes. When it comes to PRA in dogs, they are born with normal vision but by the age of 4-5 they go totally blind with no treatment. According to the release, by identifying the canines carrying this disease before they lose vision, this can be then used as a tool to guide breeding decisions to prevent the passing of the disease onto puppies.1 Historically, owners did not realize their dog had PRA until they were middle-aged, which means it could have been passed on to puppies if they had bred, making this a hard disease to control. “Once the dog’s eyesight starts to fail there’s no treatment ...
Post a Comment
Read more