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CRISPR Gene Knockout

 CRISPR Gene Knockout

CRISPR Gene Knockout is a genome-editing technique used to permanently inactivate (knock out) a specific gene to study its function or model genetic diseases. It is based on the CRISPR–Cas system, where a guide RNA (gRNA) directs the Cas nuclease to a targeted DNA sequence, creating a double-strand break. The cell repairs this break through non-homologous end joining (NHEJ), often introducing insertions or deletions that disrupt the gene. CRISPR gene knockout is widely used in functional genomics, biomedical research, drug discovery, and disease modeling due to its precision, efficiency, and scalability.

CRISPR Gene Knockout, CRISPR-Cas9, Genome Editing, Gene Disruption, Guide RNA, Cas Nuclease, DNA Double-Strand Break, NHEJ, Functional Genomics, Loss-of-Function, Gene Editing Technology

#CRISPR #GeneKnockout #GenomeEditing #CRISPRCas9 #FunctionalGenomics #GeneEditing #MolecularBiology #Biotechnology #GeneticEngineering

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