Myoepithelial Carcinoma
Myoepithelial carcinoma is a rare and aggressive malignant tumor arising from myoepithelial cells, most commonly affecting the salivary glands, particularly the parotid gland, though it can also occur in soft tissues, breast, lung, and skin. The tumor is characterized by diverse histological patterns, including spindle, plasmacytoid, epithelioid, and clear cells, often showing infiltrative growth and cellular atypia. Clinically, myoepithelial carcinoma may present as a painless, slowly enlarging mass but has a significant potential for local recurrence and distant metastasis. Diagnosis relies on histopathology supported by immunohistochemical markers such as S-100, cytokeratins, p63, calponin, and smooth muscle actin. Surgical excision with clear margins is the primary treatment, often combined with radiotherapy in advanced or recurrent cases. Early detection and accurate pathological assessment are critical for improving patient outcomes.
Myoepithelial carcinoma, salivary gland cancer, rare malignant tumor, head and neck oncology, myoepithelial cells, soft tissue sarcoma, immunohistochemistry, parotid gland tumor
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