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Holocentric Chromosomes

Holocentric Chromosomes

Holocentric chromosomes are chromosomes in which the centromere is not localized to a single region but instead spread along the entire length of the chromosome, allowing microtubules to attach at multiple points during cell division. This structure provides several evolutionary advantages, including enhanced tolerance to chromosomal breaks, efficient segregation of chromosome fragments, and greater flexibility in karyotype evolution. Holocentricity is found in diverse species such as nematodes (e.g., Caenorhabditis elegans), certain insects (Lepidoptera), some plants, and a few algae, highlighting its role as an adaptive strategy that promotes genomic stability and resilience under environmental stress.

Holocentric chromosomes, Diffuse centromere, Kinetochore distribution, Chromosome segregation, Chromosomal evolution, C. elegans chromosomes, Lepidoptera cytogenetics, Genomic stability, Centromere architecture, Chromosomal break tolerance

#HolocentricChromosomes, #DiffuseCentromere, #ChromosomeBiology, #Cytogenetics, #GenomeEvolution, #ChromosomeSegregation, #Kinetochore, #GenomicStability, #CellDivision, #EvolutionaryGenetics

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