International Genetics and Genomics of Diseases

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Brain Development Psychology

Brain Development Psychology Brain Development Psychology is a specialized field of psychology that examines how the human brain grows, matures, and changes across the lifespan, with a strong focus on infancy, childhood, and adolescence. It explores the relationship between neural development and cognitive, emotional, social, and behavioral functioning. This discipline integrates insights from neuroscience , developmental psychology, and cognitive science to understand how genetics, environment, learning, and experience shape brain structure and function. Research in brain development psychology plays a critical role in identifying developmental milestones, understanding neurodevelopmental disorders , and informing educational practices, mental health interventions, and public health policies aimed at promoting healthy brain development . Brain development psychology, developmental neuroscience, cognitive development, neural maturation, child brain development, adolescent brain, ...

Zoonotic Diseases

Zoonotic Diseases Zoonotic diseases are infectious diseases that are naturally transmitted between animals and humans. These diseases can be caused by bacteria, viruses, parasites, or fungi and may spread through direct contact with animals, consumption of contaminated food or water, bites from insects or animals, or environmental exposure. Common examples include rabies , avian influenza, Ebola, COVID-19 , brucellosis , and Lyme disease. Zoonotic diseases pose significant global public health challenges due to factors such as climate change, deforestation, wildlife trade, intensive farming, and increased human-animal interaction. Effective prevention and control rely on surveillance, vaccination, biosecurity, food safety, and the One Health approach integrating human, animal, and environmental health. Zoonotic diseases, zoonoses, animal-to-human transmission, emerging infectious diseases, One Health, zoonotic infections, wildlife diseases, public health #ZoonoticDiseases #Zoo...

Anti Immunity Disease

Anti Immunity Disease Anti-immunity diseases, commonly referred to as autoimmune diseases, occur when the immune system mistakenly identifies the body’s own cells , tissues , or organs as foreign and mounts an immune response against them. This abnormal immune activation leads to chronic inflammation, tissue damage, and functional impairment of affected organs . Anti-immunity diseases can target specific organs-such as the pancreas in type 1 diabetes or the joints in rheumatoid arthritis-or involve multiple systems, as seen in systemic lupus erythematosus. Genetic predisposition , environmental triggers, infections, and immune regulatory defects all contribute to disease development. Understanding immune tolerance, autoantibodies, and inflammatory pathways has been critical in advancing diagnostics and developing targeted immunotherapies aimed at controlling disease activity and improving patient quality of life. Anti-immunity disease, Autoimmune disorders, Immune dysregulation...

Coronary Artery Disease

Coronary Artery Disease Coronary Artery Disease (CAD) is a chronic cardiovascular condition characterized by the narrowing or blockage of the coronary arteries due to the buildup of atherosclerotic plaques composed of cholesterol, fatty deposits, calcium, and inflammatory cells . This process reduces blood flow and oxygen supply to the heart muscle, leading to clinical manifestations such as chest pain (angina), shortness of breath, myocardial infarction (heart attack), heart failure, and sudden cardiac death. Major risk factors include hypertension, diabetes mellitus, dyslipidemia, smoking, obesity, physical inactivity, advancing age, and genetic predisposition . CAD remains a leading cause of morbidity and mortality worldwide. Early diagnosis, lifestyle modification, pharmacological therapy, and interventional procedures such as angioplasty or coronary artery bypass grafting are critical for prevention, management, and improved long-term outcomes. Coronary Artery Disease, At...

Metabolic Syndrome

Metabolic Syndrome Metabolic syndrome is a complex cluster of interrelated metabolic disorders that significantly increase the risk of cardiovascular disease, type 2 diabetes mellitus, and stroke. It is characterized by a combination of central obesity, insulin resistance, hypertension, dyslipidemia (elevated triglycerides and reduced HDL cholesterol), and impaired glucose tolerance. The condition is driven by genetic predisposition, sedentary lifestyle, unhealthy dietary patterns, and chronic low-grade inflammation. Metabolic syndrome has become a major global public health concern due to its strong association with obesity, aging populations , and urbanization. Early diagnosis, lifestyle modification, and targeted medical interventions are critical for reducing long-term morbidity and mortality. Metabolic syndrome, insulin resistance, obesity, dyslipidemia, hypertension, type 2 diabetes, cardiovascular risk, chronic inflammation, glucose intolerance, metabolic disorders #Meta...

Anti Tumor Immunity

Anti Tumor Immunity Anti-tumor immunity refers to the body’s natural and therapeutic immune responses that recognize and eliminate cancer cells . It involves both innate and adaptive immune mechanisms, including cytotoxic T lymphocytes , natural killer (NK) cells, dendritic cells, macrophages, and immune signaling molecules such as cytokines and chemokines. These components work together to detect tumor-associated antigens, overcome immune evasion strategies used by cancer cells, and suppress tumor growth and metastasis. Advances in cancer immunology have led to transformative therapies—such as immune checkpoint inhibitors, cancer vaccines, adoptive cell therapies, and monoclonal antibodies—that harness or enhance anti-tumor immunity to improve patient outcomes. Anti-tumor immunity, cancer immunology, immune surveillance, T cell activation, natural killer cells, tumor antigens, immune checkpoints, immunotherapy, tumor microenvironment, immune evasion #AntiTumorImmunity, #Cance...