Gene discovery revolutionizes the detection and treatment of prostate cancer Genetic studies reveal how PSA variations affect prostate cancer detection and outcomes, paving the way for personalized diagnostic tools and care. Prostate cancer is the second most common cancer affecting men globally, with diagnostic methods and risk assessment remaining a challenge despite decades of research. For years, the prostate-specific antigen (PSA) blood test has been a cornerstone in detecting prostate cancer However, while PSA testing has been shown to reduce prostate cancer-related deaths, it also leads to over-diagnosis. This calls for a shift toward more individualized and informed approaches to screening, especially for younger men. PSA’s biological role goes beyond its use as a diagnostic marker. It plays a critical role in liquefying semen and tumor progression by interacting with growth factors and proteins in the extracellular matrix. This activity promotes cancer cell migration, bone met...